Nature. 1989 May 25;339(6222):275-80.

Cyclin synthesis drives the early embryonic cell cycle.

Source

Department of Biochemistry and Biophysics, School of Medicine, University of California, San Francisco 94143-0448.

Abstract

We have produced extracts of frog eggs that can perform multiple cell cycles in vitro. Destruction of the endogenous messenger RNA arrests the extracts in interphase. The addition of exogenous cyclin mRNA is sufficient to produce multiple cell cycles. The newly synthesized cyclin protein accumulates during each interphase and is degraded at the end of each mitosis.

PMID:: 2566917; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. [Nature. 1989]
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity.
Murray AW, Solomon MJ, Kirschner MW. Nature. 1989 May 25; 339(6222):280-6.
Cyclin synthesis and degradation and the embryonic cell cycle. [J Cell Sci Suppl. 1989]
Cyclin synthesis and degradation and the embryonic cell cycle.
Murray AW. J Cell Sci Suppl. 1989; 12:65-76.
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. [Cell. 1989]
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis.
Minshull J, Blow JJ, Hunt T. Cell. 1989 Mar 24; 56(6):947-56.
Review Simple and complex cell cycles. [Annu Rev Cell Biol. 1989]
Review Simple and complex cell cycles.
Cross F, Roberts J, Weintraub H. Annu Rev Cell Biol. 1989; 5:341-96.
Review Maturation promoting factor, cyclin and the control of M-phase. [Curr Opin Cell Biol. 1989]
Review Maturation promoting factor, cyclin and the control of M-phase.
Hunt T. Curr Opin Cell Biol. 1989 Apr; 1(2):268-74.

See reviews... See all...

Cited by over 100 PubMed Central articles

Synergistic Effect of Hyperglycemia and p27(kip1) Suppression on Adult Mouse Islet Beta Cell Replication. [Int J Endocrinol. 2012]
Synergistic Effect of Hyperglycemia and p27(kip1) Suppression on Adult Mouse Islet Beta Cell Replication.
Chen ST, Fu SH, Hsu S, Huang YY, Hsu BR. Int J Endocrinol. 2012; 2012:417390. Epub 2012 Mar 12.
Punctuated cyclin synthesis drives early embryonic cell cycle oscillations. [Mol Biol Cell. 2012]
Punctuated cyclin synthesis drives early embryonic cell cycle oscillations.
Kang Q, Pomerening JR. Mol Biol Cell. 2012 Jan; 23(2):284-96. Epub 2011 Nov 30.
Cyclin B1 expression regulated by cytoplasmic polyadenylation element binding protein in astrocytes. [J Neurosci. 2011]
Cyclin B1 expression regulated by cytoplasmic polyadenylation element binding protein in astrocytes.
Kim KC, Oh WJ, Ko KH, Shin CY, Wells DG. J Neurosci. 2011 Aug 24; 31(34):12118-28.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cyclin synthesis drives the early embryonic cell cycle.
Cyclin synthesis drives the early embryonic cell cycle.
Nature. 1989 May 25 ;339(6222):275-80.

PubMed
Hibernation in a monotreme, the echidna (Tachyglossus aculeatus).
Hibernation in a monotreme, the echidna (Tachyglossus aculeatus).
Comp Biochem Physiol A Comp Physiol. 1989 ;92(4):609-12.

PubMed
In search of cellular mechanisms of memory.
In search of cellular mechanisms of memory.
Prog Neurobiol. 1989 ;32(4):277-349.

PubMed
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.
N Engl J Med. 1989 Jun 1 ;320(22):1446-52.

PubMed
Effects of hydroxychloroquine and sulphasalazine on progression of joint damage ...
Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis.
Lancet. 1989 May 13 ;1(8646):1036-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Cyclin synthesis drives the early embryonic cell cycle.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by over 100 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information