Association of pulmonary silicosis and systemic sclerosis

BMJ Case Rep. 2015 Jan 27:2015:bcr2013202509. doi: 10.1136/bcr-2013-202509.

Abstract

The Erasmus syndrome describes the association of generalised systemic sclerosis following exposure to silica with or without silicosis. This is a case report on a male patient presenting with this syndrome. Radiological changes of silicosis have preceded the diagnosis of systemic sclerosis by 6 years and occupational exposure has been stopped. The clinical features did not differ from systemic sclerosis in general. The evolution was marked by a progression of skin lesions whereas pulmonary lesion remained stable.

Publication types

  • Case Reports

MeSH terms

  • Disease Progression
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology*
  • Male
  • Middle Aged
  • Occupational Diseases / complications*
  • Occupational Diseases / pathology
  • Occupational Exposure / adverse effects*
  • Radiography
  • Risk Factors
  • Scleroderma, Systemic / etiology*
  • Scleroderma, Systemic / pathology
  • Silicon Dioxide / adverse effects*
  • Silicosis / complications*
  • Silicosis / pathology
  • Skin / pathology*
  • Syndrome

Substances

  • Silicon Dioxide