Cancer of the sigmoid colon and antibodies. A puzzle

Transfus Apher Sci. 2015 Apr;52(2):220-1. doi: 10.1016/j.transci.2014.12.025. Epub 2014 Dec 23.

Abstract

In this work we describe the case report of a woman affected by cancer of the sigmoid colon and with a positive direct antiglobulin test (DAT) and indirect antiglobulin test (IAT). Case report with results: A meticulous medical history showed that the woman had been suffering from recurrent fetal loss. Then she had cardiac and coagulative problems. These data suggested a phospholipid syndrome.

Conclusion: The patient had a medical history positive for a phospholipid syndrome and we think that this disease could explain the onset of the autoantibody.

Keywords: Autoantibody; Autoimmune hemolitic anemia; Cancer of the sigmoid colon; Phospholipids; Syndrome.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Habitual
  • Aged, 80 and over
  • Anemia, Hemolytic, Autoimmune / complications
  • Antibodies / blood*
  • Antiphospholipid Syndrome / complications
  • Autoantibodies / blood
  • Blood Coagulation Disorders / complications
  • Cardiovascular Diseases / complications
  • Colon, Sigmoid / immunology*
  • Colon, Sigmoid / pathology*
  • Colonoscopy
  • Coombs Test
  • Female
  • Humans
  • Sigmoid Neoplasms / diagnosis*
  • Sigmoid Neoplasms / immunology*

Substances

  • Antibodies
  • Autoantibodies