Triglyceride-rich lipoproteins and coronary artery disease risk: new insights from human genetics

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):e3-9. doi: 10.1161/ATVBAHA.114.305172. Epub 2015 Jan 8.

Authors

Sumeet A Khetarpal¹, Daniel J Rader²

Affiliations

¹ From the Departments of Genetics and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
² From the Departments of Genetics and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia. rader@mail.med.upenn.edu.

PMID: 25573854
DOI: 10.1161/ATVBAHA.114.305172

No abstract available

Keywords: apolipoprotein AV, human; apolipoprotein C-III; coronary artery disease; exome; myocardial infarction; triglycerides.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apolipoprotein A-V
Apolipoprotein C-III / blood
Apolipoprotein C-III / genetics
Apolipoproteins A / blood
Apolipoproteins A / genetics
Biomarkers / blood
Coronary Artery Disease / blood*
Coronary Artery Disease / drug therapy
Coronary Artery Disease / genetics*
Drug Design
Genetic Predisposition to Disease
Humans
Hypolipidemic Agents / therapeutic use
Lipoprotein Lipase / blood
Lipoprotein Lipase / genetics
Lipoproteins / blood*
Lipoproteins / genetics*
Molecular Targeted Therapy
Mutation
Phenotype
Risk Factors
Triglycerides / blood*
Up-Regulation

Substances

APOA5 protein, human
Apolipoprotein A-V
Apolipoprotein C-III
Apolipoproteins A
Biomarkers
Hypolipidemic Agents
Lipoproteins
Triglycerides
LPL protein, human
Lipoprotein Lipase

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