Am J Clin Pathol. 1989 Oct;92(4):509-12.

Signet ring cell sinus histiocytosis. A previously unrecognized histologic condition mimicking metastatic adenocarcinoma in lymph nodes.

Gould E, Perez J, Albores-Saavedra J, Legaspi A.

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Department of Pathology, University of Miami-Jackson Memorial Hospital, Florida.

Abstract

The axillary lymph nodes in a radical mastectomy specimen from a 70-year-old insulin-dependent diabetic patient contained significantly vacuolated sinus histiocytes. The histologic picture closely resembled metastatic signet ring cell adenocarcinoma. The signet ring histiocytes did not stain with the mucicarmine or periodic acid-schiff stains or any of the immunohistochemical epithelial markers. The differential diagnosis and the possible origin of these vacuolated histiocytes are discussed.

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Am J Clin Pathol. 1990 Dec;94(6):800-1.

PMID:: 2552795; [PubMed - indexed for MEDLINE]

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Signet ring cell sinus histiocytosis. A previously unrecognized histologic condi...
Signet ring cell sinus histiocytosis. A previously unrecognized histologic condition mimicking metastatic adenocarcinoma in lymph nodes.
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Signet ring cell sinus histiocytosis. A previously unrecognized histologic condition mimicking metastatic adenocarcinoma in lymph nodes.

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