Abstract
Alkalating chemotherapeutic agents are frequently implicated in the development of acute non-lymphocytic leukemia. A case report illustrates the danger of administering a prolonged course of adjuvant chemotherapy with Melphalan following mastectomy for breast cancer.
MeSH terms
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Breast Neoplasms / drug therapy*
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Carcinoma, Intraductal, Noninfiltrating / drug therapy*
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Chromosome Deletion
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Chromosomes, Human, Pair 7
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Female
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Humans
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Leukemia, Myelomonocytic, Acute / chemically induced*
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Leukemia, Myelomonocytic, Acute / drug therapy
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Melphalan / adverse effects*
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Middle Aged
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Risk Factors
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Time Factors