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J Pharm Belg. 1989 Jan-Feb;44(1):71-83.

[Stereostructure-activity relation of morphinics. Topology of the mu receptor and nature of the opioid pharmacophore].

[Article in French]

Abstract

The perspective of this essay is to issue a stereostructure-activity relationship analysis of opioid compounds in terms of the topology of P et T subsites of the mu receptor. Emphasis is put on the dichotomic nature of the opioid pharmacophore made of pharmacons and tensors.

PMID:
2542515
[PubMed - indexed for MEDLINE]
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