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Br J Haematol. 2015 Mar;168(6):806-10. doi: 10.1111/bjh.13221. Epub 2014 Nov 17.

Survival of AIDS-related diffuse large B-cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma in the German HIV Lymphoma Cohort.

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  • 1First Department of Internal Medicine, University of Cologne, Cologne, Germany.

Abstract

Overall survival (OS) of patients with acquired immunodeficiency syndrome (AIDS)-related Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL) and plasmablastic lymphoma (PBL) was analysed in the German AIDS-related-Lymphoma-Cohort-Study. Of 291 patients prospectively included between January 2005 and December 2012, 154 had DLBCL, 103 BL and 34 PBL. Two-year OS rates were similar between BL (69%) and DLBCL patients (63%) but lower for PBL patients (43%). Intermediate (Hazard ratio [HR] 4·1 95% confidence interval [CI] 1·98-8·49) or high (HR 4·92 95% CI 2·1-11·61) International Prognostic Index, bone marrow involvement (HR 1·69 95% CI 1·00-2·84) and PBL histology (HR 2·24 95% CI 1·24-4·03) were independent predictors of mortality.

© 2014 John Wiley & Sons Ltd.

KEYWORDS:

AIDS-related Burkitt lymphoma; AIDS-related diffuse large B-cell-lymphoma; AIDS-related lymphoma; AIDS-related plasmablastic lymphoma; lymphoma

PMID:
25403997
[PubMed - indexed for MEDLINE]
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