Immunization of epidemics in multiplex networks

PLoS One. 2014 Nov 17;9(11):e112018. doi: 10.1371/journal.pone.0112018. eCollection 2014.

Abstract

Up to now, immunization of disease propagation has attracted great attention in both theoretical and experimental researches. However, vast majority of existing achievements are limited to the simple assumption of single layer networked population, which seems obviously inconsistent with recent development of complex network theory: each node could possess multiple roles in different topology connections. Inspired by this fact, we here propose the immunization strategies on multiplex networks, including multiplex node-based random (targeted) immunization and layer node-based random (targeted) immunization. With the theory of generating function, theoretical analysis is developed to calculate the immunization threshold, which is regarded as the most critical index for the effectiveness of addressed immunization strategies. Interestingly, both types of random immunization strategies show more efficiency in controlling disease spreading on multiplex Erdös-Rényi (ER) random networks; while targeted immunization strategies provide better protection on multiplex scale-free (SF) networks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Epidemics*
  • Humans
  • Immunization*
  • Models, Theoretical*

Grants and funding

This paper was supported by the National Natural Science Foundation of China (No. 61202362, 61262057, 61472433; URLs http://www.nsfc.gov.cn/; L. H. W. and S. D. L. received the funding), the Project funded by China Postdoctoral Science Foundation (No. 2013M542560; URLs http://jj.chinapostdoctor.org.cn/V1/Program1/Default.aspx; L. S. D. received the funding), the Natural Science Foundation of Shandong Province (No. ZR2013FM025, ZR2013FQ001, ZR2011FQ030; URLs http://www.sdnsf.gov.cn/portal/; L. H. W. received the funding), and the Shandong Academy of Sciences Youth Fund Project (No. 2013QN007; URLs http://www.sdnsf.gov.cn/portal/; L. H. W. received the funding). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.