Characteristics of secundum atrial septal defects not percutaneously closed

Catheter Cardiovasc Interv. 2015 Feb 1;85(2):234-9. doi: 10.1002/ccd.25700. Epub 2014 Oct 29.

Abstract

Objectives: We sought to review our single center experience with secundum atrial septal defect (ASD) device closure, evaluating the incidence and morphological characteristics where percutaneous closure was thought inappropriate.

Material and methods: All children assessed as unsuitable for transcatheter device closure were reviewed. Data collected included: demographics, defect morphology by echocardiography or at cardiac catheterization and defect size focusing on the reasons for procedural deferral.

Results: Between January 2002 and December 2010, 639 children underwent closure of an isolated secundum ASD: 82 children (13%) where referred directly to surgery, 43 (6%) were thought unsuitable for device closure at the time of catheterization and underwent subsequent surgery and the remaining 514 (81%) underwent successful device closure including 2 on a second attempt. The reasons for pursuing a surgical closure (n = 124, mean age = 5.7 years; range: 0.6-17.4 years; defect diameter/body weight = 1.39) included: the need for a device thought too large for implantation versus the child's size (n = 51), defects with deficient rim(s) (n = 48), multiple defects (n = 7), defects sized >36 mm (n = 2), malposition (n = 2), ECG changes (n = 3), aneurysmal IAS (n = 2), sinus venosus (n = 2), or others (n = 7).

Conclusion: The reasons for deferring transcatheter device closure of a secundum ASD are diverse, not only isolated rim deficiencies but the requirements of large implants, malposition, arrhythmias, and lack of hemodynamic need are influential components in clinical decision making.

Keywords: congenital heart disease; interventional cardiology; pediatric cardiac catheterization.

MeSH terms

  • Adolescent
  • Age Factors
  • Body Weight
  • Cardiac Catheterization / instrumentation*
  • Cardiac Surgical Procedures / instrumentation*
  • Child
  • Child, Preschool
  • Contraindications
  • Echocardiography
  • Female
  • Heart Septal Defects, Atrial / diagnosis
  • Heart Septal Defects, Atrial / surgery*
  • Humans
  • Infant
  • Male
  • Ontario
  • Patient Selection
  • Prosthesis Design
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Septal Occluder Device*
  • Treatment Outcome

Supplementary concepts

  • Atrial Septal Defect, Secundum Type