Reproducibility of quantitative 99Tcm-MAG 3 measurements in rats

Nucl Med Commun. 1989 Jun;10(6):431-4. doi: 10.1097/00006231-198906000-00009.

Abstract

Repetitive quantitative renal extraction studies of 99Tcm-MAG 3, performed in nine rats, demonstrated excellent reproducibility of successive measurements. These results are better than with 99Tcm-DTPA, due to the higher renal extraction of the 99Tcm-MAG 3. The % of renal uptake 10 min after the injection was not influenced by the elapsed time between the end of the 99Tcm-MAG 3 preparation and its i.v. administration.

MeSH terms

  • Animals
  • Kidney / diagnostic imaging*
  • Kidney / metabolism
  • Male
  • Metabolic Clearance Rate*
  • Oligopeptides / pharmacokinetics*
  • Organometallic Compounds / pharmacokinetics*
  • Rats
  • Rats, Inbred Strains
  • Technetium Tc 99m Mertiatide
  • Tomography, Emission-Computed*

Substances

  • Oligopeptides
  • Organometallic Compounds
  • Technetium Tc 99m Mertiatide