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J Child Neurol. 2015 Sep;30(10):1381-7. doi: 10.1177/0883073814550656. Epub 2014 Sep 30.

The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps.

Author information

  • 1Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA
  • 2Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • 3Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • 4Department of Neurology, University of California, San Francisco, CA, USA Department of Pediatrics, Benioff Children's Hospitals, San Francisco, CA, USA.
  • 5Pediatric MS Center at Loma Linda University Children's Hospital, Loma Linda, CA, USA.
  • 6Lourie Center for Pediatric MS, Stony Brook Children's Hospital, Stony Brook, NY, USA.
  • 7Partners MS Center, Harvard Medical School, Boston, MA, USA.
  • 8Pediatric Multiple Sclerosis and Related Diseases Program, Boston Children's Hospital, Boston, MA, USA.
  • 9Blue Bird Circle Multiple Sclerosis Center, Texas Children's Hospital, Houston, TX, USA.
  • 10UAB Center for Pediatric Onset Demyelinating Disease, Children's Hospital of Alabama, Birmingham, AL, USA.
  • 11Mayo Clinic's Pediatric MS Center, Rochester, MN, USA.
  • 12Pediatric Multiple Sclerosis Center, Jacobs Neurological Institute, SUNY Buffalo, Buffalo, NY, USA.
  • 13Department of Neurology, University of California, San Francisco, CA, USA.


Multiple sclerosis and other demyelinating diseases in the pediatric population have received an increasing level of attention by clinicians and researchers. The low incidence of these diseases in children creates a need for the involvement of multiple clinical centers in research efforts. The Network of Pediatric Multiple Sclerosis Centers was created initially in 2006 to improve the diagnosis and care of children with demyelinating diseases. In 2010, the Network shifted its focus to multicenter research while continuing to advance the care of patients. The Network has obtained support from the National Multiple Sclerosis Society, the Guthy-Jackson Charitable Foundation, and the National Institutes of Health. The Network will continue to serve as a platform for conducting impactful research in pediatric demyelinating diseases of the central nervous system. This article provides a description of the history and development, organization, mission, research priorities, current studies, and future plans of the Network.

© The Author(s) 2014.


NPMSC; demyelinating disease; multicenter research; multiple sclerosis; network

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