Cardiovascular and autonomic responses to whole-body cryostimulation in essential hypertension

Cryobiology. 2014 Oct;69(2):249-55. doi: 10.1016/j.cryobiol.2014.07.014. Epub 2014 Aug 6.

Abstract

Over recent years, a considerable increase in the popularity of cryostimulation and whole body cryotherapy (WBC) procedures has occurred both among healthy individuals and in various groups of patients, including those with primary untreated hypertension. The aim of this study was to compare the effects of WBC on the functional parameters of cardiovascular system in normotensive and primarily hypertensive individuals. The study included 26 young male volunteers with normal blood pressure range (NormoBP) and 13 with essential arterial hypertension (HyperBP). Each subject was exposed to cryotherapeutic factor (whole-body cryotherapy/cryostimulation, WBC) at a temperature of approximately -115°C to -125°C for a period of 3 min. The cardiovascular and autonomic parameters were measured noninvasively with Task Force® Monitor. Measurements in a supine position and tilt test were performed "before WBC" and "after WBC". Our study revealed that cryogenic temperatures exert strong modulatory effect on the cardiovascular system. Both groups showed adaptive changes of myocardial and vascular parameters in response to rapid cooling of virtually the whole body surface. While the profiles of some of these changes were similar in both the groups, also several considerable intergroup differences were documented. Consequently, the cryostimulation and cryotherapy treatment should be prescribed carefully to individuals who present with cardiovascular failure of any degree.

Keywords: Baroreceptors; Cryotherapeutics safety; Hypertension; Whole-body cryostimulation.

MeSH terms

  • Adult
  • Baroreflex
  • Blood Pressure
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System / physiopathology
  • Cryotherapy / methods*
  • Essential Hypertension
  • Humans
  • Hypertension / physiopathology
  • Hypertension / therapy*
  • Male
  • Middle Aged
  • Young Adult