Effect of chlorhexidine chip in the treatment of chronic periodontitis

J Nat Sci Biol Med. 2014 Jul;5(2):268-72. doi: 10.4103/0976-9668.136159.

Abstract

Aims: The evaluation of clinical and specific microbiological changes associated with chlorhexidine chip in the chronic periodontitis patients.

Materials and methods: A total of 30 chronic periodontitis patients (aged 20-65 years) having pocket depth of ≥5 mm in molar teeth were selected and randomly divided into following treatment groups: Group 1 - Scaling and root planning (SRP), Group 2 - SRP along with chlorhexidine chip and Group 3 - Only chlorhexidine chip. The clinical and microbial parameters were recorded at baseline and 1 and 3 months post-treatment as above. Benzoyl-DL-arginine-naphthylamide (BANA) chair side test was used for estimation of specific microbiota.

Results: Gingival index, probing pocket depth and clinical attachment level scores in selected teeth within the groups at different time intervals was significantly (P < 0.001) different. Although, the comparison between groups for specific microbiota in selected sites at different intervals was not statistically significant at baseline and 1 month, it reached statistical significance at 3(rd) month post-treatment. Although significant reductions in percentage of BANA positive sites were observed in all three groups, the Group 2 had significantly greater percentage of BANA negative sites.

Conclusion: Local drug delivery using chlorhexidine chip enhances the benefit of SRP in the treatment of chronic periodontitis.

Keywords: N Benzoyl-DL-arginine-β naphthylamide; chlorhexidine; chronic periodontitis; local drug delivery.