Profound hypoglycemia-ınduced by vaccinium corymbosum juice and laurocerasus fruit

Indian J Pharmacol. 2014 Jul-Aug;46(4):446-7. doi: 10.4103/0253-7613.135963.

Abstract

An emergency intervention was performed in a 75-year-old male patient with hypoglycemic attack and blackout. Although he was diagnosed with prediabetes before 2 years, he did not take any anti-diabetic drug or follow dietary advice. He drank Vaccinium corymbosum L (VC) juice daily with a belief that it increases sexual potency. Before the development of hypoglycemia, the patient had consumed about 500 ml VC juice in addition to eating 200-300 gram of Laurocerasus officinalis (LO) fruit. The measured plasma glucose (PG) level during loss of consciousness was 30 mg/dl. The profound hypoglycemia may be an unexpected side effect of an interaction between the chemical compositions of the two plants, occurred as a result of LO fruit intake that may have a strong PG-lowering effect or related to excessive intake of VC juice. Both plants may be considered in the alternative treatment of diabetes.

Keywords: Hypoglycemia; Laurocerasus officinalis; vaccinium corymbosum L.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Beverages / adverse effects*
  • Blood Glucose / analysis
  • Drug Interactions
  • Fruit / adverse effects
  • Glucose / administration & dosage
  • Glucose / therapeutic use
  • Humans
  • Hypoglycemia / blood
  • Hypoglycemia / chemically induced*
  • Hypoglycemia / drug therapy
  • Male
  • Rosaceae / adverse effects*
  • Treatment Outcome
  • Unconsciousness / blood
  • Unconsciousness / chemically induced
  • Unconsciousness / drug therapy
  • Vaccinium / adverse effects*

Substances

  • Blood Glucose
  • Glucose