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Acad Radiol. 2014 Nov;21(11):1411-5. doi: 10.1016/j.acra.2014.05.024. Epub 2014 Aug 1.

Usefulness of coronal reconstruction CT images for quantitative evaluation of the cross-sectional area of small pulmonary vessels.

Author information

  • 1Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa 216-8511, Japan. Electronic address: shin4114@mac.com.
  • 2Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa 216-8511, Japan; Department of Radiology, Graduate School of Medical Science, University of the Ryukyu.
  • 3Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa 216-8511, Japan.

Abstract

RATIONALE AND OBJECTIVES:

Cross-sectional area <5 mm(2) (CSA<5) is a computed tomography (CT) metric that has been used for the evaluation of pulmonary vessel alterations and perfusion. CSA<5 is calculated from three axial slices; thus, whether CSA<5 represents the small pulmonary vessel alterations in the whole lung remains unclear. The purpose of this study was to compare the measurements of CSA<5 using three axial slices and coronal reconstructed slices in the relationship between the measured CSA<5 and pulmonary perfusion measured using lung perfusion scintigraphy.

MATERIALS AND METHODS:

This study comprised 28 subjects who underwent both noncontrast CT and lung perfusion scintigraphy. The present study measured CSA<5 using both three axial CT images and coronal reconstruction images and then obtained the percentage of the CSA in right lung to that in whole lung (R/W-CSA<5). Using anteroposterior and posteroanterior projections on technetium-99m macroaggregated albumin (MAA) lung perfusion scintigraphy, we obtained right and total lung counts and calculated the percentage of the right to whole lung counts (R/W-MAA). The correlations of the R/W-CSA<5 calculated using three axial slices (R/W-CSA(A)x<5) and coronal reconstructed slices (R/W-CSA(COR)<5) with R/W-MAA were evaluated using Spearman rank correlation analysis.

RESULTS:

Both R/W-CSA(Ax)<5 and R/W-CSA(COR)<5 were significantly correlated with R/W-MAA; however, the correlation coefficient with R/W-CSA(COR)<5 (ρ = 0.842, P < .0001) was greater than that with R/W-CSA(Ax)<5 (ρ = 0.631, P = .0004).

CONCLUSIONS:

Coronal reconstruction images appear suitable for quantitative measurement of CSA of small pulmonary vessels.

Copyright © 2014 AUR. Published by Elsevier Inc. All rights reserved.

KEYWORDS:

Pulmonary vessels; computed tomography; pulmonary perfusion; quantitative; reconstruction

[PubMed - indexed for MEDLINE]
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