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BMJ. 1989 Jul 22;299(6693):228-30.

Influence of maternal diet during lactation and use of formula feeds on development of atopic eczema in high risk infants.

Author information

  • 1Memorial University of Newfoundland, Janeway Child Health Centre, Canada.

Erratum in

  • BMJ 1989 Oct 7;299(6704):896.

Abstract

OBJECTIVE:

To examine the effects of maternal diet during lactation and the use of formula feeds on the development of atopic eczema in infants at risk.

DESIGN:

Mothers who planned to breast feed exclusively were randomly allocated to either a restricted diet (avoiding milk and other dairy products, eggs, fish, peanuts, and soybeans) or a diet without restrictions. Mothers who did not plan to breast feed were randomly allocated to using one of three formula feeds.

SETTING:

Child health centre in Canada.

SUBJECTS:

97 Mothers who chose to breast feed and 124 mothers who did not.

INTERVENTIONS:

Restricted diet for 49 mothers who breast fed. Casein hydrolysate formula, soy milk formula, or cows' milk formula for infants not breast fed.

MAIN OUTCOME MEASURE:

Development of eczema in babies.

RESULTS:

Infants were followed up over 18 months and examined for eczema. Eczema was less common and milder in babies who were breast fed and whose mothers were on a restricted diet (11/49 (22%) v 21/48 (48%)). In infants fed casein hydrolysate, soy milk, or cows' milk 9/43 (21%), 26/41 (63%), and 28/40 (70%), respectively, developed atopic eczema.

CONCLUSIONS:

In families with a history of atopic disease [corrected] mothers who breast feed should avoid common allergenic foods during lactation. If they choose not to breast feed a hydrolysate formula should be used.

PMID:
2504375
[PubMed - indexed for MEDLINE]
PMCID:
PMC1836914
Free PMC Article
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