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Turk J Haematol. 2014 Jun;31(2):111-20. doi: 10.4274/tjh.2014.0103. Epub 2014 Jun 10.

Recommendations for the Treatment of Invasive Fungal Infections in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-1).

Author information

  • 1Ankara University Faculty of Medicine Cebeci Campus, Department of Hematology, Ankara, Turkey.
  • 2İstanbul University Cerrahpaşa Faculty of Medicine, Department of Hematology, İstanbul, Turkey.
  • 3Istanbul University Cerrahpasa Faculty of Medicine, Department of Infectious Diseases, İstanbul, Turkey.
  • 4İstanbul University Istanbul Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, İstanbul, Turkey.
  • 5Uludağ University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Bursa, Turkey.
  • 6Florence Nightingale Hospital, Hematology Unit, İstanbul, Turkey.
  • 7Uludağ University Faculty of Medicine, Department of Hematology, Bursa, Turkey.
  • 8Trakya University Faculty of Medicine, Department of Hematology, Edirne, Turkey.

Abstract

in English, Turkish

The introduction of novel antifungal agents for the treatment of invasive fungal disease in hematological malignancies and also changing treatment strategies have had a great impact in managing affected patients. The medical literature includes some important clinical studies that are being used as evidence for guidelines. The problem with these studies and the guidelines is that they are not very easy to interpret, they include controversial issues, and they are not easy to apply to every patient or country. This paper was designed to critically show the main problems associated with these approaches and provide important information that will help Turkish doctors to adopt them in daily clinical practice.

KEYWORDS:

Antifungal treatment; Evidence; Hematological malignancies; invasive fungal infection

PMID:
25035667
[PubMed]
PMCID:
PMC4102037
Free PMC Article

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