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Curr Opin Plant Biol. 2014 Jul 14;21C:51-58. doi: 10.1016/j.pbi.2014.06.006. [Epub ahead of print]

Diversity and specificity: auxin perception and signaling through the TIR1/AFB pathway.

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  • 1Section of Cell and Developmental Biology and Howard Hughes Medical Institute, UCSD, La Jolla, CA 92093, United States.
  • 2Section of Cell and Developmental Biology and Howard Hughes Medical Institute, UCSD, La Jolla, CA 92093, United States. Electronic address: mestelle@ucsd.edu.

Abstract

Auxin is a versatile plant hormone that plays an essential role in most aspects of plant growth and development. Auxin regulates various growth processes by modulating gene transcription through a SCFTIR1/AFB-Aux/IAA-ARF nuclear signaling module. Recent work has generated clues as to how multiple layers of regulation of the auxin signaling components may result in diverse and specific response outputs. In particular, interaction and structural studies of key auxin signaling proteins have produced novel insights into the molecular basis of auxin-regulated transcription and may lead to a refined auxin signaling model.

Copyright © 2014 Elsevier Ltd. All rights reserved.

PMID:
25032902
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