Development of angioimmunoblastic T-cell lymphoma after treatment of diffuse large B-cell lymphoma: a case report and review of literature

Int J Clin Exp Pathol. 2014 May 15;7(6):3432-8. eCollection 2014.

Abstract

Cases of diffuse large B-cell lymphoma (DLBCL) arising after the initial diagnosis of angioimmunoblastic T-cell lymphoma (AITL) and DLBCL synchronous with AITL have been reported. To date, there is no report on the subsequent development of AITL in patients with DLBCL. Here we presented a rare case of AITL developing six months after the initial diagnosis of DLBCL. In order to investigate the clinical and molecular features of patients with AITL and DLBCL, we also reviewed the literature on AITL patients developing DLBCL, and patients with composite AITL and DLBCL.

Keywords: Angioimmunoblastic T-cell lymphoma; composite lymphoma; diffuse large B-cell lymphoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Humans
  • Immunoblastic Lymphadenopathy / pathology*
  • Immunophenotyping
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Lymphoma, T-Cell / pathology*
  • Male
  • Neoplasms, Second Primary / pathology*