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Oncol Rep. 2014 Sep;32(3):922-6. doi: 10.3892/or.2014.3315. Epub 2014 Jul 9.

New enhanced and effective method for staging cancer to detect lymph nodes after fat-dissociation.

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  • 1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
  • 2Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.

Abstract

Pathologic staging is a key factor in the treatment and outcome of cancer patients, and lymph node status plays a pivotal role in this staging process. Several methods of lymph node assessment, such as the fat clearance, Schwartz solution and GEWF solution, are unpopular as they require a significant amount of time (1‑9 days) to clear the fat of the resected mesentery and to visualize the lymph nodes. In the present study, we discussed a more simple and effective method, called the fat‑dissociation method, which clears the fat using enzymes and allows for easy identification of lymph nodes around vessels. This new procedure facilitates precise staging of cancer which directs the post-operative treatment plan.

PMID:
25017814
[PubMed - indexed for MEDLINE]
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