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Cell Metab. 2014 Jul 1;20(1):2-4. doi: 10.1016/j.cmet.2014.06.007.

Rejuvenation: it's in our blood.

Author information

  • 1Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA.
  • 2Department of Pathology, University of Washington, Seattle, WA 98195-7470, USA. Electronic address: kaeber@uw.edu.

Abstract

It has been known for some time that blood from young mice can positively impact aged animals, while blood from old mice has the opposite effect. Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects.

Copyright © 2014 Elsevier Inc. All rights reserved.

PMID:
24988454
[PubMed - indexed for MEDLINE]
PMCID:
PMC4126586
[Available on 2015-07-01]
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