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Chem Biol. 2014 Jun 19;21(6):703-4. doi: 10.1016/j.chembiol.2014.06.001.

Timing protein assembly in neurons.

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  • 1Department of Biotechnology & Biophysics, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. Electronic address: m.sauer@uni-wuerzburg.de.

Abstract

Integration of two fluorescence imaging methods enables tracking of the formation of fibrillar Aβ peptide amyloid aggregates in neurons, as discussed by Esbjörner and colleagues in this issue of Chemistry & Biology. This approach has the potential to fundamentally improve our understanding of the onset and therapeutic intervention of neurodegenerative diseases.

Copyright © 2014 Elsevier Ltd. All rights reserved.

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