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Int J Psychiatry Clin Pract. 2005;9(3):157-67. doi: 10.1080/13651500510029138.

The relationship between depression and cardiovascular disease.

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  • 1Department of Clinical and Biomedical Sciences: Barwon Health, The University of Melbourne, Victoria, Australia.


Evidence from epidemiological studies has established that depression is a risk factor for the development of cardiovascular disease (CVD) and that the comorbidity of depression with pre-existing CVD worsens the prognosis for sufferers of CVD. Depression has also been associated with other behaviours that impact on CVD, such as medication non-compliance, and an unwillingness to adopt an exercise program, that reduce the likelihood of successful rehabilitation from CVD. Published literature on the current knowledge of the association between depression and CVD is reviewed in this paper.


Depression; cardiovascular; myocardial infarction

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