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Am J Public Health. 2014 Aug;104(8):e101-5. doi: 10.2105/AJPH.2014.302044. Epub 2014 Jun 12.

Mortality from sexually transmitted diseases in reproductive-aged women: United States, 1999-2010.

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  • 1Kara A. McElligott is with the Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill.



I estimated the sexually transmitted disease-related mortality among US reproductive-aged women from 1999 to 2010.


I estimated mortality from National Center for Health Statistics' Multiple Cause of Death data. I defined reproductive age as 15 to 44 years. For diseases partially caused by sexual transmission, I estimated the proportion attributable to sexual transmission from the literature. To calculate mortality rates, I estimated number of deaths from each disease and Census Bureau population for reproductive-aged women for 1999 to 2010.


From 1999 to 2010, the cumulative sexually transmitted disease-related mortality rate decreased by 49%, from 5.3 to 2.7 deaths per 100 000. The primary contributors were HIV and human papilloma virus infections. Mortality from sexually transmitted HIV infection decreased by 62%, from 3.4 to 1.3 deaths per 100 000. Mortality from human papilloma virus-associated gynecologic cancers decreased by 19%, from 1.6 deaths per 100 000 in 1999 to 1.3 deaths per 100 000 in 2010.


Screening and treatment for sexually transmitted diseases may reduce mortality. Research is needed to determine whether sexually transmitted disease-related morbidity among reproductive-aged women has decreased over the past decade.

[PubMed - indexed for MEDLINE]
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