Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Int J Surg. 2014;12 Suppl 1:S173-7. doi: 10.1016/j.ijsu.2014.05.016. Epub 2014 May 22.

Gastroesophageal reflux disease and obesity: Do we need to perform reflux testing in all candidates to bariatric surgery?

Author information

  • 1Department of Surgery, Second University of Naples, Via Pansini 5, 80131 Naples, Italy. Electronic address: salvatore.tolone@unina2.it.
  • 2Department of Surgery, Second University of Naples, Via Pansini 5, 80131 Naples, Italy.



Obesity is a strong independent risk factor of gastroesophageal reflux disease (GERD) symptoms and esophageal erosions. However the relationship between obesity and GERD is still a subject of debate. In fact, if in most cases bariatric surgery can diminish reflux by losing a large amount of fat, on the other hand some restrictive procedure can worsen or cause the presence of GERD. Thus, it is unclear if patients candidate to bariatric surgery have to perform pre-operative reflux testing or not.


of the study was to verify the presence of GERD patterns in patients candidate to surgery and the need of pre-operative reflux testing.


All patients underwent to a standardized questionnaire for symptoms severity (GERQ), upper endoscopy, high resolution manometry (HRiM) and impedance pH-monitoring (MII-pH). Patients were stratified into: group 1 (negative for both GERQ and endoscopy), group 2 (positive for GERQ and negative for endoscopy), group 3 (positive for both GERQ and endoscopy). A healthy-volunteers group (HV) was assessed.


One hundred thirty-nine subjects (obese, 124; HV normal weight, 15) were studied. Group 1 showed comparable mean LES pressure, peristaltic function, bolus transport and presence of hiatal hernia than HV. Group 2 showed a reduction of these parameters, while group 3 showed a statistical significant reduction in LES pressure, peristaltic function, bolus transport and increase in presence of hiatal hernia. At MII-pH, Group 1 showed a not significant increase in reflux patterns; group 2 and 3 showed a significant increase in esophageal acid exposure and in number of refluxes (both acid and weakly acid), with group 3 showing the higher grade of reflux pattern.


Obese subjects with pre-operative presence of GERD symptoms and endoscopical signs could be tested with HRM and MII-pH before undergoing bariatric surgery, especially for restrictive procedures. On the other hand, obese patients without any sign of GERD could not be tested for reflux, showing similar patterns to HV.

Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.


Bariatric surgery; GERD; High resolution manometry; Impedance-pH; Obesity

[PubMed - in process]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk