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Neuropsychobiology. 1989;22(3):150-69.

Salivary cortisol in psychobiological research: an overview.

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  • 1Department of Clinical and Physiological Psychology, University of Trier, FRG.


The measurement of cortisol in saliva provides the basic scientist as well as the clinician with a reliable tool for investigations of hypothalamus-pituitary-adrenal axis activity. Since saliva samples can be obtained stress-free and independent from medically trained personnel this method may be well suited for use in psychobiological studies. This overview intends to give a comprehensive introduction to the method of salivary cortisol assessment and to briefly discuss its application in different scientific disciplines.

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