Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Electrocardiol. 2014 Apr 18. pii: S0022-0736(14)00133-2. doi: 10.1016/j.jelectrocard.2014.04.010. [Epub ahead of print]

Impact of catheter ablation on P-wave parameters on 12-lead electrocardiogram in patients with atrial fibrillation.

Author information

  • 1Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
  • 2Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA. Electronic address: kheist@mgh.harvard.edu.

Abstract

BACKGROUND:

Catheter ablation has emerged as a widely used treatment modality for atrial fibrillation (AF). P-wave abnormalities have been described in the patients with AF, and catheter ablation may potentially further impact P-wave parameters due to ablation of atrial tissue.

METHODS:

We reviewed data on P-wave parameters (P-wave duration, amplitude and P-wave duration and amplitude product) in leads V1 and aVF and changes in the P-terminal force (Ptf; product of duration and amplitude of terminal part of P-wave) in lead V1 from 12-lead electrocardiograms obtained prior to and after CA of a total of 46 (28 paroxysmal and 18 persistent) AF patients.

RESULTS:

The median age of patients in our study was 63 (range: 30-77) years. We noticed a significant reduction in the P-wave duration (from 87.39±28.62ms at baseline to 72.09±24.59ms; p=0.0072) and the product of P-wave duration and amplitude in lead V1 (12.16±5.54mVms at baseline to 8.30±5.78mVms, p=0.0015) after CA. There was also a significant decrease in P-wave duration (from 92.57±19.67ms at baseline to 76.48±16.32ms after CA, p=0.0001) and P-wave duration and amplitude product in lead aVF (12.61±4.05mVms at baseline to 9.77±3.86mVms after CA, p=0.0001). CA also led to a significant decrease in Ptf (from 4.56±1.88 at baseline to 2.85±1.42mVms, p<0.0001).

CONCLUSION:

Radiofrequency catheter ablation of AF leads to modification of P-wave parameters with substantial diminution in both the amplitude and duration of the P-wave in leads V1 and aVF. This likely represents reduction in electrically active atrial tissue after ablation, and may serve as a marker for the extent of ablated atrial tissue.

Copyright © 2014 Elsevier Inc. All rights reserved.

KEYWORDS:

Atrial fibrillation; Catheter ablation; Electrocardiogram

PMID:
24850319
[PubMed - as supplied by publisher]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk