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Cardiovasc J Afr. 2014 Mar-Apr;25(2):73-7. doi: 10.5830/CVJA-2014-009.

Intra-uterine growth restriction as a risk factor for hypertension in children six to 10 years old.

Author information

  • 1Department of Children's Cardiology and Rheumatology of the 2nd Chair of Paediatrics, Medical University of Lodz, Poland. agazamek@gmail.com.
  • 2Department of Children's Cardiology and Rheumatology of the 2nd Chair of Paediatrics, Medical University of Lodz, Poland.
  • 3Institute of Information Technology, Lodz University of Technology, Poland.

Abstract

INTRODUCTION:

Intra-uterine growth restriction (IUGR) is present in about 3-10% of live-born newborns and it is as high as 20-30% in developing countries. Since the 1990s, it has been known that abnormalities during foetal growth may result in cardiovascular disease, including hypertension in adulthood.

METHODS:

This study evaluated blood pressure parameters (using ambulatory blood pressure monitoring) in children aged six to 10 years old, born as small for gestational age (SGA), and compared them to their healthy peers born as appropriate for gestational age (AGA).

RESULTS:

In the SGA group, an abnormal blood pressure level (prehypertension or hypertension) was present significantly more often than in the AGA group (50 vs 16%, p < 0.01). This relationship also occurred in association with the type of IUGR (asymmetric p < 0.01, symmetric p < 0.05).

CONCLUSIONS:

In SGA children, abnormal blood pressure values occurred more frequently than in AGA children.

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