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Anesth Pain Med. 2014 Mar 14;4(2):e15499. doi: 10.5812/aapm.15499. eCollection 2014.

Postoperative Management of Shivering: A Comparison of Pethidine vs. Ketamine.

Author information

  • 1Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran.
  • 2Liver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • 3Faculty of Paramedical, Tabriz University of Medical Sciences, Tabriz, Iran.
  • 4Department of Anesthesiology, Rasoul Akram Medical Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Abstract

BACKGROUND:

One of the unpleasant side effects of general anesthesia is shivering in the process of recovery. It is an involuntary oscillatory mechanical movement that can be classified as clonic movements. These movements can affect one or several groups of skeletal muscles beginning from 5 to 30 minutes after the discontinuation of anesthesia.

OBJECTIVES:

We aimed to study ketamine's effect on shivering after operation compared to pethidine as a way for treatment of postoperative shivering.

PATIENTS AND METHODS:

In this study, 60 patients who underwent ENT surgery with general anesthesia and had shivering during recovery were randomly divided into two groups of 30 patients each receiving ketamine (0.2 mg/kg IV) and pethidine (0.5 mg/kg).

RESULTS:

There was no statistically significant difference between the shivering intensity in both groups. Only regarding the shivering in the first minute after entering the recovery room, there was an obvious difference between ketamine and pethidine groups which was again not statistically significant (P = 0.07).

CONCLUSIONS:

The results of this study showed that ketamine and pethidine are both equally effective in the reduction of postoperative shivering.

KEYWORDS:

Anesthesia; Ketamine; Meperidine; Pethidine; Shivering

PMID:
24829883
[PubMed]
PMCID:
PMC4013503
Free PMC Article
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