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J Assoc Physicians India. 2013 Aug;61(8):558-9.

Single glucose challenge test procedure for diagnosis of gestational diabetes mellitus: a Jammu cohort study.



To elucidate an evidence based Single Glucose Challenge test to diagnose Gestational Diabetes Mellitus (GDM).


This study included 500 pregnant women in 16-32 weeks of gestation. They underwent 75g Oral Glucose Challenge test irrespective of the last meal timing and 2 hr venous blood was drawn. After 3 days they underwent 75g OGTT in the fasting state and their 2 hr blood was drawn. Plasma glucose was estimated in both samples by GOD-POD method. GDM was diagnosed with 2hr Plasma glucose (PG) > or = 7.8 mmol/l (> or = 140 mg/dl) based on WHO criteria. The data was analysed by computer software Microsoft excel for windows and epi-info version 6.0, CDC, Atlanta, GA.


Among 500 women, 55(11%) were diagnosed as GDM by WHO criteria. It was observed that there was no statistical difference (p > 0.05) between 2 hr PG of GCT and 2 hr PG of WHO recommended method.


This Single Glucose Challenge test procedure is cost-effective, evidence based and patient friendly approach to diagnosis Gestational Diabetes Mellitus.

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