Emergence of plasmid-mediated quinolone resistance genes in clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in Henan, China

Xiaobing Jiang; Tao Yu; Xiaojie Jiang; Wei Zhang; Laiping Zhang; Jianmin Ma

doi:10.1016/j.diagmicrobio.2014.03.025

Emergence of plasmid-mediated quinolone resistance genes in clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in Henan, China

Diagn Microbiol Infect Dis. 2014 Jul;79(3):381-3. doi: 10.1016/j.diagmicrobio.2014.03.025. Epub 2014 Apr 12.

Authors

Xiaobing Jiang¹, Tao Yu², Xiaojie Jiang³, Wei Zhang⁴, Laiping Zhang⁴, Jianmin Ma¹

Affiliations

¹ College of Life Sciences, Henan Normal University, Xinxiang 453007, China.
² Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China. Electronic address: yutao7777@hotmail.com.
³ College of Chemistry and Molecular Engineering, Henan Provincial Key Laboratory of Chemical Biology and Organic Chemistry, Zhengzhou University, Zhengzhou 450000, China.
⁴ Department of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453000, China.

PMID: 24805186
DOI: 10.1016/j.diagmicrobio.2014.03.025

Abstract

A total of 216 clinical isolates of Acinetobacter baumannii and Pseudomonas aeruginosa were collected from a general hospital in Henan, China, and screened for the plasmid-mediated quinolone resistance (PMQR) determinants. The presence of β-lactamase genes and mutations in quinolone resistance-determining regions were investigated among the PMQR-positive isolates.

Keywords: Acinetobacter baumannii; PMQR; Pseudomonas aeruginosa; QRDRs.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acinetobacter Infections / microbiology
Acinetobacter baumannii / drug effects*
Acinetobacter baumannii / isolation & purification
Anti-Bacterial Agents / pharmacology*
China
Drug Resistance, Bacterial*
Genes, Bacterial
Hospitals, General
Humans
Microbial Sensitivity Tests
Plasmids*
Pseudomonas Infections / microbiology
Pseudomonas aeruginosa / drug effects*
Pseudomonas aeruginosa / isolation & purification
Quinolones / pharmacology*
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Quinolones
beta-Lactamases