[Extracorporeal therapy of patients with liver disease in the intensive care unit]

Med Klin Intensivmed Notfmed. 2014 May;109(4):246-51. doi: 10.1007/s00063-013-0321-4. Epub 2014 Apr 27.
[Article in German]

Abstract

Acute and acute-on-chronic liver failure are often associated with development of organ failure. Its occurrence is associated with high morbidity and mortality. Extracorporeal replacement therapies are frequently necessary in these patient populations. Replacement therapies can be divided into renal replacement therapies and liver support therapies. These therapies consist of artificial liver support systems (i.e., MARS(®) system, Prometheus(®)), which are able to remove water-soluble and albumin-bound toxins, and of bioartifical liver support systems. This manuscript provides a review of current practice in the extracorporeal support of patients with liver diseases in the intensive care unit.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Critical Care / methods*
  • Humans
  • Intensive Care Units*
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / diagnosis
  • Liver Cirrhosis / therapy
  • Liver Failure / diagnosis
  • Liver Failure / etiology
  • Liver Failure / therapy*
  • Liver, Artificial*
  • Multiple Organ Failure / diagnosis
  • Multiple Organ Failure / etiology
  • Multiple Organ Failure / therapy*
  • Renal Replacement Therapy*