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Cell. 2014 Apr 24;157(3):534-8. doi: 10.1016/j.cell.2014.03.009.

Siri of the cell: what biology could learn from the iPhone.

Author information

  • 1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • 2Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: trey@bioeng.ucsd.edu.

Abstract

Modern genomics is very efficient at mapping genes and gene networks, but how to transform these maps into predictive models of the cell remains unclear. Recent progress in computer science, embodied by intelligent agents such as Siri, inspires an approach for moving from networks to multiscale models able to predict a range of cellular phenotypes and answer biological questions.

Copyright © 2014 Elsevier Inc. All rights reserved.

PMID:
24766803
[PubMed - indexed for MEDLINE]
PMCID:
PMC4154484
Free PMC Article
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