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J Gastric Cancer. 2014 Mar;14(1):54-7. doi: 10.5230/jgc.2014.14.1.54. Epub 2014 Mar 31.

Gastric carcinoma with bone marrow metastasis: a case series.

Author information

  • 1Department of Medical Oncology, Ankara Onkoloji Training and Research Hospital, Ankara, Turkey.

Abstract

Gastric cancer is a major cause of cancer-related mortality. At the time of diagnosis, majority of the patients usually have unresectable or metastatic disease. The most common sites of metastases are the liver and the peritoneum, but in the advanced stages, there may be metastases to any region of the body. Bone marrow is an important metastatic site for solid tumors, and the prognosis in such cases is poor. In gastric cancer cases, bone marrow metastasis is usually observed in younger patients and in those with poorly differentiated tumors. Prognosis is worsened owing to the poor histomorphology as well as the occurrence of pancytopenia. The effect of standard chemotherapy is unknown, as survival is limited to a few weeks. This report aimed to evaluate 5 gastric cancer patients with bone marrow metastases to emphasize the importance of this condition.

KEYWORDS:

Bone marrow metastasis; Poor prognosis; Stomach neoplasms

PMID:
24765538
[PubMed]
PMCID:
PMC3996250
Free PMC Article
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