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Neuron. 2014 Apr 16;82(2):256-7. doi: 10.1016/j.neuron.2014.03.033.

How to grow a synapse.

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  • 1Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA.
  • 2Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA. Electronic address: bernardo_sabatini@hms.harvard.edu.

Abstract

Activity-dependent alterations in the strength of an individual glutamatergic synapse are often accompanied by changes in the size and shape of the postsynaptic terminal. Two studies in this issue of Neuron, Meyer et al. (2014) and Bosch et al. (2014), shed new light on the mechanisms and signaling pathways underlying structural long-term potentiation.

Copyright © 2014 Elsevier Inc. All rights reserved.

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