Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Int Assoc Provid AIDS Care. 2014 Nov-Dec;13(6):526-8. doi: 10.1177/2325957414531454. Epub 2014 Apr 16.

Incidence of Kaposi's sarcoma and associated mortality in Fresno, California, 1998 to 2012.

Author information

  • 1Fresno Medical Education Program, University of California San Francisco, Fresno, CA, USA amu@fresno.ucsf.edu.
  • 2Fresno County Department of Public Health, Fresno, CA, USA.
  • 3Fresno Medical Education Program, University of California San Francisco, Fresno, CA, USA.

Abstract

OBJECTIVE:

The incidence of Kaposi's sarcoma (KS) decreased dramatically after the introduction of highly active antiretroviral therapy (HAART). This study determined the ongoing incidence of and mortality from KS in HIV-infected adults from 1998-2012 in Fresno County, California. The role of virologic control and immune reconstitution was assessed.

METHODS:

Incident cases were identified from the state Electronic HIV/AIDS Reporting System (EHARS), the California Cancer Registry, and hospital records of the county HIV treatment center.

RESULTS:

From 1998-2012, the average incidence of KS was 0.51 cases per 100,000 person-years. Of the 66 cases of KS there were 20 deaths, with 85% of the mortality occurring in the first 12 months. Among patients on HAART achieving HIV RNA <400 copies/uL, but with a <50 cell/uL increase in CD4 count there was no improvement in mortality.

CONCLUSIONS:

The incidence of KS remains stable since 1998 with a 12-month mortality of 30%.

© The Author(s) 2014.

KEYWORDS:

HIV/AIDS; Kaposi's sarcoma; highly active antiretroviral therapy; incidence; mortality

PMID:
24739208
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk