Send to:

Choose Destination
See comment in PubMed Commons below
J Int Assoc Provid AIDS Care. 2014 Nov-Dec;13(6):526-8. doi: 10.1177/2325957414531454. Epub 2014 Apr 16.

Incidence of Kaposi's sarcoma and associated mortality in Fresno, California, 1998 to 2012.

Author information

  • 1Fresno Medical Education Program, University of California San Francisco, Fresno, CA, USA
  • 2Fresno County Department of Public Health, Fresno, CA, USA.
  • 3Fresno Medical Education Program, University of California San Francisco, Fresno, CA, USA.



The incidence of Kaposi's sarcoma (KS) decreased dramatically after the introduction of highly active antiretroviral therapy (HAART). This study determined the ongoing incidence of and mortality from KS in HIV-infected adults from 1998-2012 in Fresno County, California. The role of virologic control and immune reconstitution was assessed.


Incident cases were identified from the state Electronic HIV/AIDS Reporting System (EHARS), the California Cancer Registry, and hospital records of the county HIV treatment center.


From 1998-2012, the average incidence of KS was 0.51 cases per 100,000 person-years. Of the 66 cases of KS there were 20 deaths, with 85% of the mortality occurring in the first 12 months. Among patients on HAART achieving HIV RNA <400 copies/uL, but with a <50 cell/uL increase in CD4 count there was no improvement in mortality.


The incidence of KS remains stable since 1998 with a 12-month mortality of 30%.

© The Author(s) 2014.


HIV/AIDS; Kaposi's sarcoma; highly active antiretroviral therapy; incidence; mortality

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk