Double trouble? Progranulin mutation and C9ORF72 repeat expansion in a case of primary non-fluent aphasia

J Neurol Sci. 2014 Jun 15;341(1-2):176-8. doi: 10.1016/j.jns.2014.03.030. Epub 2014 Mar 19.
No abstract available

Keywords: C9ORF72; Frontotemporal lobar degeneration (FTLD); Primary non-fluent aphasia (PNFA); Progranulin (GRN).

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Cerebral Cortex / diagnostic imaging
  • Cerebral Cortex / pathology
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Intercellular Signaling Peptides and Proteins / genetics*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Middle Cerebral Artery / physiopathology
  • Mutation / genetics*
  • Positron-Emission Tomography
  • Primary Progressive Nonfluent Aphasia / diagnosis
  • Primary Progressive Nonfluent Aphasia / genetics*
  • Progranulins
  • Radiography
  • Spin Labels

Substances

  • GRN protein, human
  • Intercellular Signaling Peptides and Proteins
  • Progranulins
  • Spin Labels
  • Fluorodeoxyglucose F18