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Am J Trop Med Hyg. 2014 Jun;90(6):1180-3. doi: 10.4269/ajtmh.14-0048. Epub 2014 Mar 31.

Detection and phylogenetic characterization of a case of Histoplasma capsulatum infection in mainland China.

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  • 1Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China; Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
  • 2Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China; Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China panweihua@medmail.com.cn jungusmmu@gmail.com.

Abstract

Histoplasmosis usually occurs in specific endemic areas. Sporadic cases have also been reported in mainland China. Here, we described an indigenous case of disseminated histoplasmosis. Phylogenetic analysis revealed that the Histoplasma capsulatum isolated in our case belongs to the Australian clade. Combined with previous studies, it revealed high genetic diversity among Chinese H. capsulatum isolates.

© The American Society of Tropical Medicine and Hygiene.

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