Malignant acanthosis nigricans, florid cutaneous papillomatosis and tripe palms syndrome associated with gastric adenocarcinoma

Marta Stawczyk-Macieja; Aneta Szczerkowska-Dobosz; Roman Nowicki; Hanna Majewska; Michał Dubowik; Małgorzata Sokołowska-Wojdyło

doi:10.5114/pdia.2014.40663

Malignant acanthosis nigricans, florid cutaneous papillomatosis and tripe palms syndrome associated with gastric adenocarcinoma

Postepy Dermatol Alergol. 2014 Feb;31(1):56-8. doi: 10.5114/pdia.2014.40663. Epub 2014 Feb 25.

Authors

Marta Stawczyk-Macieja¹, Aneta Szczerkowska-Dobosz¹, Roman Nowicki¹, Hanna Majewska², Michał Dubowik³, Małgorzata Sokołowska-Wojdyło¹

Affiliations

¹ Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman Nowicki MD, PhD.
² Department of Pathology, Medical University of Gdansk, Poland. Head of Department: Prof. Wojciech Biernat MD, PhD.
³ Department of Gastroenterology, Medical University of Gdansk, Poland. Head of Department: Prof. Marian Smoczyński MD, PhD.

Abstract

Malignant acanthosis nigricans is a rare paraneoplastic skin syndrome mostly associated with gastric adenocarcinoma. Florid cutaneous papillomatosis and tripe palms syndrome are considered to be abortive clinical variants of acanthosis nigricans. Clinical manifestations include pruritic, hyperkeratotic and hyperpigmented plaques with a subsequent formation of velvety papillomas in the involved areas. This case report describes an unusual case of the patient diagnosed with a combination of malignant acanthosis nigricans, florid cutaneous papillomatosis and tripe palms syndrome associated with gastric adenocarcinoma.

Keywords: acanthosis nigricans; paraneoplastic skin syndrome; tripe palms.

Publication types

Case Reports