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    Nature. 1989 Apr 13;338(6216):557-62.

    Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.

    Source

    Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.

    Abstract

    Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo.

    PMID:
    2467210
    [PubMed - indexed for MEDLINE]

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