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Hua Xi Kou Qiang Yi Xue Za Zhi. 2014 Feb;32(1):45-50.

[Preliminary study of assessment of mental health level among oral tumor patients and difference of relevant material basis].

[Article in Chinese]

Abstract

OBJECTIVE:

To investigate the difference in mental health status of oral tumor patients and their spouses, and explore the differences on the basis of relevant materials.

METHODS:

Forty patients with oral cancer, eighteen spouses, and thirty-five patients with oral benign tumor were diagnosed in the West China Hospital of Stomatology between December 2011 and August 2012 and assessed with symptom checklist-90 (SCL90) (the 5-grade scoring). Participants were assessed independently according to their conditions. Blood samples were obtained from the participants by syringe on the second admission day. A method was developed to determine the concentrations of catecholamine and glucocorticoid in the serum using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

RESULTS:

The scores for compel, depression and rests in the cancer group and benign tumor group were statistically significant (P<0.05). The scores for compel, dread and stubborn in the cancer group and their spouses were statistically significant (P<0.05). The differences between the total and other monomial factor scores were not statistically significant. However, the contents of epinephrine, norepinephrine, cortisone and hydrocortisone in the serum, as determined by HPLC-MS/MS, were significantly different (P<0.001).

CONCLUSION:

Psychiatric factors do not show a simple factor effect on patients. Symptoms of patients may be based on tumorigenesis and developed in small molecules. Further research is required.

PMID:
24665640
[PubMed - in process]
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