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Dent Clin North Am. 2014 Apr;58(2):341-9. doi: 10.1016/j.cden.2013.12.005.

Chemotherapy or radiation-induced oral mucositis.

Author information

  • 1Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA. Electronic address: Lalla@uchc.edu.
  • 2Department of Dental Oncology, Northeast Cancer Centre, Health Sciences North, Northern Ontario School of Medicine, 41 Ramsey Lake Road, Sudbury, ON P3E 5J1, Canada.
  • 3Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA.

Abstract

Oral mucositis is a significant toxicity of systemic chemotherapy and of radiation therapy to the head and neck region. The morbidity of oral mucositis can include pain, nutritional compromise, impact on quality of life, alteration in cancer therapy, risk for infection, and economic costs. Management includes general symptomatic support and targeted therapeutic interventions for the prevention or treatment of oral mucositis. Evidence-based clinical practice guidelines are available to guide clinicians in the selection of effective management strategies.

Copyright © 2014 Elsevier Inc. All rights reserved.

KEYWORDS:

Cancer; Chemotherapy; Oral mucositis; Radiation therapy; Stomatitis

PMID:
24655526
[PubMed - indexed for MEDLINE]
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