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Microvascular anastomosis using polyethylene glycol 4000 and fibrin glue.
Department of Dermatology, Osaka University School of Medicine, Japan.
Rat femoral arteries and veins were anastomosed using fibrin glue and a soluble intravascular stent made of polyethylene glycol 4000 (PEG-4000) with a patency rate of 100%. The anastomoses were strong enough to tolerate a pressure of 250 cm H2O. Histological changes at anastomosed sites and toxicity of PEG-4000 were also examined. With this method, an end-to-end anastomosis can be performed easily and quickly.
PMID: 2465054 [PubMed - indexed for MEDLINE]
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