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Chem Commun (Camb). 2014 May 4;50(34):4438-41. doi: 10.1039/c4cc00752b. Epub 2014 Mar 19.

A sensitive colorimetric and fluorescent sensor based on imidazolium-functionalized squaraines for the detection of GTP and alkaline phosphatase in aqueous solution.

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  • 1Key Laboratory of Green Chemistry, Technology of Ministry of Education, College of Chemistry, State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, PR China.


Imidazolium-functionalized squaraine ImSQ8 is synthesized as a sensitive colorimetric and fluorescent chemosensor for GTP in aqueous solution. The detection limit of GTP reaches 5.4 ppb. Its applications in the live-cell imaging and enzyme activity assay have also been demonstrated.

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