Secular trends of low birthweight and macrosomia and related maternal factors in Beijing, China: a longitudinal trend analysis

BMC Pregnancy Childbirth. 2014 Mar 18:14:105. doi: 10.1186/1471-2393-14-105.

Abstract

Background: Information tracking changes of birthweight is scarce in China. To examine trends of low birthweight (birthweight < 2500 g) and macrosomia (birthweight ≥ 4000 g) and potential risk factors in Beijing, hospital records from two major obstetrics and gynecology hospitals in urban districts in Beijing were analyzed.

Methods: Hospital records from 1996 to 2010 were retrieved. Information of prenatal examination and birth outcomes was entered into a structured database. Live births were used for trend analysis. Information of live births in 2010 was used to identify potential risk factors.

Results: A total of 63 661 live births were delivered during 1996-2010 in the study hospitals. The average birthweight increased from 3271 g in 1996 to 3 359 g in 2000 and slightly declined to 3 331 in 2010. The percentage of low birthweight fluctuated around 4.0%. No significant increase or decrease was observed. Preterm birth was the main cause of low birthweight, accounting for more than 73% of low birthweight. The average percentage of macrosomia was 7.6%. The percentages of macrosomia increased from 6.6% in 1996 to 9.5% in 2000 and declined to 7.0% in 2010. Excessive gestational weight gain and gestational diabetes were significantly associated with macrosomia.

Conclusions: Continuously monitoring abnormal birthweight is needed and intervention should focus on appropriate gestational weight gain and reduction of preterm birth and gestational diabetes.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • China / epidemiology
  • Diabetes, Gestational / epidemiology*
  • Female
  • Fetal Macrosomia / diagnosis
  • Fetal Macrosomia / epidemiology*
  • Fetal Macrosomia / etiology
  • Follow-Up Studies
  • Gestational Age
  • Humans
  • Incidence
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature, Diseases / epidemiology
  • Infant, Premature, Diseases / etiology*
  • Male
  • Pregnancy
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Weight Gain