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Pediatr Neurol. 2014 Apr;50(4):411-6. doi: 10.1016/j.pediatrneurol.2014.01.003. Epub 2014 Jan 6.

Kleine-Levin syndrome: a case report and review of literature.

Author information

  • 1Department of Psychiatry and Sleep Clinic, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India.
  • 2Department of Psychiatry and Sleep Clinic, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India. Electronic address: guptaravi_2003@yahoo.co.in.
  • 3Department of Radiology, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India.

Abstract

BACKGROUND:

Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently.

METHOD:

We report a male adolescent who presented with recurrent hypersomnia, hypersexuality, and hyperorality. Magnetic resonance imaging of the brain and overnight polysomnography followed by a multiple sleep latency tests were ordered. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale.

RESULTS:

Magnetic resonance imaging of the brain did not reveal any abnormality. Overnight video-synchronized polysomnography and multiple sleep latency tests ruled out narcolepsy. Epworth Sleepiness Scale score at baseline was 22. He was prescribed lithium carbonate 300 mg twice a day. The symptoms improved within a week after starting lithium carbonate therapy.

CONCLUSION:

Kleine-Levin syndrome may present with hyperorality, and our patient responded well to lithium carbonate therapy.

Copyright © 2014 Elsevier Inc. All rights reserved.

KEYWORDS:

Kleine-Levin syndrome; adolescent; lithium; recurrent hypersomnia

PMID:
24630285
[PubMed - indexed for MEDLINE]
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