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Cell Host Microbe. 2014 Mar 12;15(3):255-9. doi: 10.1016/j.chom.2014.02.013.

Endogenous retroviruses and human cancer: is there anything to the rumors?

Author information

  • 1Department of Molecular Biology and Microbiology, Graduate Program in Molecular Microbiology, Sackler School of Graduate Biomedical Sciences, Tufts University, 136 Harrison Avenue, Boston, MA 02111, USA.
  • 2Department of Molecular Biology and Microbiology, Graduate Program in Molecular Microbiology, Sackler School of Graduate Biomedical Sciences, Tufts University, 136 Harrison Avenue, Boston, MA 02111, USA. Electronic address: john.coffin@tufts.edu.

Abstract

Xenotropic murine leukemia virus-related virus (XMRV) infection was incorrectly associated with prostate cancer and chronic fatigue syndrome (CFS) in recent years. In this forum, we discuss the story of XMRV and how we can apply lessons learned here to inform the debate surrounding cancers associated with human endogenous retroviruses (HERVs).

Copyright © 2014 Elsevier Inc. All rights reserved.

PMID:
24629332
[PubMed - indexed for MEDLINE]
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