Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe

Chem Commun (Camb). 2014 Apr 25;50(32):4211-3. doi: 10.1039/c4cc00489b.

Abstract

To create a nanoscale dual switch, two responsive DNA motifs, azobenzene-modified DNAs and G-telomeric repeat sequences, were introduced together into the nanoframe system. The dual-switching behaviors controlled by photoirradiation and K(+) were successfully visualized in real time by high-speed atomic force microscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry
  • DNA / chemistry*
  • DNA / radiation effects
  • G-Quadruplexes*
  • Microscopy, Atomic Force
  • Models, Molecular
  • Nanostructures / chemistry*
  • Nanostructures / radiation effects
  • Potassium / chemistry
  • Telomere / chemistry
  • Telomere / genetics
  • Ultraviolet Rays

Substances

  • Azo Compounds
  • DNA
  • azobenzene
  • Potassium