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Transpl Int. 2014 Aug;27(8):e70-5. doi: 10.1111/tri.12306. Epub 2014 Apr 12.

Malignant hemangiosarcoma in a renal allograft: diagnostic difficulties and clinical course after nephrectomy and immunostimulation.

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  • 1Department of Nephrology, Kantonsspital Baden, Baden, Switzerland.


Hemangiosarcomas are rare tumors of endothelial cell origin. To date, only 20 cases of hemangiosarcoma have been described after renal transplantation, occurring mostly in the skin or in a dialysis fistula. We report a primary metastasizing hemangiosarcoma arising from a renal allograft. The patient was treated with transplant nephrectomy, discontinuation of immunosuppression, and immunostimulation with pegylated interferon-α-2a and has now been in complete remission for 3 years.

© 2014 Steunstichting ESOT.


interferon; kidney neoplasms; kidney transplantation; tumor

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